2024 Ovarian granulosa cell apoptosis

Ovarian granulosa cell apoptosis

Author: kkti

August undefined, 2024

WebNov 5, 2024 · Premature ovarian failure (POF), also known as primary ovarian insufficiency, is a common cause of infertility and is characterized by hypoestrogenism, elevated gonadotropins, and amenorrhea [ 1, 2 ]. POF is a rare clinical condition that only affects about 1–5 out of 1000 women younger than 40 years [ 3 ]. WebNov 21, 2024 · The cell proliferation assay (CCK8) and flow cytometry suggested that the small-interfering RNA-induced silencing of Gpsm1 significantly increased apoptosis and …

Silica nanoparticles induce ovarian granulosa cell …

WebNov 17, 2024 · Oxidative stress leads to ovarian functional decline by inducing granulosa cell (GC) apoptosis. Circular RNA circFoxo3 acts as a critical factor in regulating cell cycle and apoptosis, and ... WebJul 26, 2024 · Primary rat ovarian granulosa cells (OGCs) were collected from ovarian tissues and identified by cell immunohistochemistry. The effects of miR-126-3p-hucMSCs-exosomes and miR-126-3p on OGCs function were determined by cell proliferation and apoptosis assays in a cisplatin induced POF cell model. javascript programiz online

MicroRNAs in ovarian follicular atresia and granulosa cell apoptosis ...

WebApr 11, 2024 · In vivo studies revealed that ADSCs transplantation reduced the apoptosis of ovarian granulosa cells and secretion of follicle-stimulating hormone. The number of total follicles, primordial follicles, primary follicles, and mature follicles and secretion of anti-Müllerian hormone and estradiol (E2) were also increased by ADSCs. WebJun 1, 2024 · Human ovarian granulosa cell line (KGN cell) was obtained from Prof. Jiangning Zhou as a gift. In previous studies, KGN cell line was considered as a very useful model that mimicked the physiological regulation of steroidogenesis, cell growth, and apoptosis in human granulosa cells [29, 30]. javascript print image from url

Granulosa Cell Apoptosis in the Ovarian Follicle—A …

Frontiers Granulosa Cell Apoptosis in the Ovarian

WebApr 1, 2024 · These results demonstrated that PS MPs could induce pyroptosis and apoptosis of ovarian granulosa cells via the NLRP3/Caspase-1 signaling pathway maybe triggered by oxidative stress. The present ... WebApr 11, 2024 · This may be because full-term PPE promotes the proliferation of pre-granulosa cells, while mid-late pregnancy exposure inhibits apoptosis of pre-granulosa cells, thus affecting the expression of CYP19 in fetal ovarian pre-granulosa cells. However, the specific mechanism needs to be further explored. javascript print image base64WebApr 10, 2024 · Furthermore, both APLN-13 and -17 improved the total antioxidant capacity of the ovarian granulosa cells, but such effects were not seen when the cells were preincubated with ML221. ... Literature demonstrated that APLN restrains cell apoptosis and retina angiogenesis and improves the proliferation of vascular smooth muscle cells, … javascript praca junior

"WebOvarian follicle atresia in all vertebrates studied to date is mediated via apoptosis, a process that is often initiated within the granulosa cell layer. While follicle atresia is … " - Ovarian granulosa cell apoptosis

Ovarian granulosa cell apoptosis

ANP promotes proliferation and inhibits apoptosis of ovarian ... - Nature

WebMar 8, 2024 · SNPs cause follicular atresia via the induction of ovarian granulosa cell apoptosis. However, the mechanisms for this phenomenon are not well understood. … WebJan 29, 2024 · Ovarian follicles are structures generated in the ovaries and have two major functions, the production of hormones and oocytes. Antral follicles regulate these functions via the inner wall of granulosa cells (GCs) that rest on a distinct basal lamina. Ovarian follicles are made up of oocytes surrounded by pre-granulosa cells or GCs.

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WebApr 5, 2024 · The regulation of granulosa cells (GCs) proliferation and apoptosis is the key step in follicular selection which determines the egg production performance of poultry. miR-202-5p has been reported to be involved in regulating the proliferation and apoptosis of mammalian ovarian GCs. However, its role in regulating the proliferation and ... WebJan 10, 2024 · The regulation of ovarian granulosa cell death by pro-and anti-apoptotic molecules. J Reprod Dev. 2006;52:695–705. Article CAS PubMed Google Scholar Manabe N, Kimura Y, Uchio K, Tajima C, Matsushita H, Nakayama M, Sugimoto M, Miyamoto H. Regulatory mechanisms of granulosa cell apoptosis in ovarian follicle atresia.

WebMay 31, 2024 · Human umbilical cord mesenchymal stem cells (huMSCs) can treat primary ovarian insufficiency (POI) related to ovarian granulosa cell (OGC) apoptosis caused by cisplatin chemotherapy.... WebAfter the adoptive transfer of Treg cells overexpressing Peli1 in autoimmune POI mice, the apoptosis rate of ovarian granulosa cells declined. The levels of the inflammatory inhibitors interleukin 10 and transforming growth factor-β as well as the ovarian hormone estradiol were elevated. The number of primordial, primary, secondary, and mature ...

WebNov 8, 2024 · Ambient particulate matters (PMs) have adverse effects in human and animal female reproductive health. Silica nanoparticles (SNPs), as a major component of PMs, can induce follicular atresia via the … WebJun 1, 2024 · The apoptosis rate of the cisplatin-induced group was significantly higher than that of the control group, indicating that the establishment of ovarian granulosa cell …

WebFeb 25, 2024 · Primary ovarian insufficiency (POI), previously known as premature ovarian failure, is characterized by the loss of ovarian function before 40 years of age. Amenorrhea, infertility, and sigs...

WebApr 1, 2015 · The resistance to apoptosis is mediated by products of several cAMP-induced anti-apoptotic genes, including inhibitor of apoptosis protein, B-cell lymphoma-extra large (BCL-X), and B-cell lymphoma-2 (BCL-2). Enhanced FSH-induced inhibitor of differentiation 2 (ID2) mRNA expression within the GC layer also occurs coincident with selection. javascript pptx to htmlWebNov 8, 2024 · Ambient particulate matters (PMs) have adverse effects in human and animal female reproductive health. Silica nanoparticles (SNPs), as a major component of PMs, … javascript progress bar animationWebThe mechanism of DON action involves the ribotoxic stress response (RSR), and it acts directly on ovarian granulosa cells to increase cell death. In ruminants, DON is metabolized to de-epoxy-DON (DOM-1), which cannot activate the RSR but has been shown to increase cell death in ovarian theca cells. ... DON increased granulosa cell … javascript programs in javatpointWebApr 11, 2024 · This may be because full-term PPE promotes the proliferation of pre-granulosa cells, while mid-late pregnancy exposure inhibits apoptosis of pre … javascript programsWebJan 9, 2014 · Aberrant ovarian granulosa cell proliferation and apoptosis may lead to granulosa cell tumors (GCT), the pathogenesis of which involves transcription factors … javascript print object as jsonWebOct 26, 2024 · Polycystic ovary syndrome (PCOS) is one of the most incident reproductive endocrine diseases, with a prevalence ranging from 5 to 10% in women of reproductive … javascript projects for portfolio redditWebJun 15, 2024 · The exclusive criteria of PCOS women; 1, diagnosed with hyperprolactinemia; 2, abnormal androgen secretion due to adrenal or ovarian tumors; 3, patients with uncorrected thyroid disease; 4, suspected Cushing’s syndrome; 5, using estrogen or oral contraceptives and other hormone drugs in recent one month; 6, using other drugs that … javascript powerpoint